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6-MAPB is a psychedelic and entactogenic drug which is structurally related to 6-APB and MDMA. It is not known to have been widely sold as a “designer drug” but has been detected in analytical samples taken from individuals hospitalised after using drug combinations that included other benzofuran derivatives.


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6-MAPB is a new research chemical that is known to be an  entactogenic  and psychedelic compound. It is related to MDMA and 6-APB  structurally,  therefore, it may have similar effects.

Manufacturers  created this product so  it could be studied to learn more about such analogs  of MDA and if the  new supplementary compound could produce the  beneficial effects without  the harmful side effects.

At this time,  there is only scientific  research data available on this research  chemical. Due to the newness of  the chemical, more research needs to be  compiled to learn if 6-MAPB may  have abuse potential or long term side  effects prior to going to  clinical trials.

Due to lack of research  6-MAPB is not intended for  human consumption.
Research on 6-MAPB  shows it to be closely related to 5-MAPB with minor  changes in the  structure. ACD/Labs conducted studies on 6-MAPB which  shows the vapor  pressure, boiling point, and other scientific data.

ChemAxon also  published predicted studies of the research chemical  including  structural calculations, names and identifiers, solubility,  and  geometry.

One other study was conducted comparing 6-MAPB and 6-APB  to learn the  identifying metabolites.

The study showed that the  metabolites were  very similar to 5-MAPB and 5-APB along with the  benzofuran and furan.

With 1-(benzofuran-6-yl)-N-methylpropan-2-amine pathways were determined the same as  with 6-APB which were  hydroxylation and benzofuran with the next step  being the cleavage of  the enzymatic ring with alcohol or reducing  carboxylic acid.

It showed  that more hydroxylated the alcohol and  carboxylic acid became  glucuronidated. The results after further study  did not show many  differences with the metabolites when comparing the  5-isomers.

The only  difference was a bit in the formation of dihydroxy  metabolites which was  nothing more than a lower rate of formation

IUPAC name
CAS Number
Chemical and physical data
Formula C12H15NO
Molar mass 189.25
3D model (JSmol)
Interactive image
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Additional information


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